李赛教授-简介

Mobil: 13628050176 ; Email：lisai@scu.edu.cn

个人简历

1994.09～1998.07四川大学，获高分子材料科学与工程学士学位

1998.09～2001.07四川大学，获生物医学工程硕士学位

2001.09～2004.07中国科学院成都有机化学研究所，获有机化学博士学位

2005.02～2007.06新加坡南洋理工大学(博士后)

2007.07至今四川大学化学化工学院；

主要研究方向：

功能高分子材料的合成和加工技术；

生物医用高分子材料，靶向药物控制缓释；

新型蒸汽热泵技术；

发表的主要论文：

1.Xiang, Hongzhao;Sun, Qiaomei;Wang, Wenjing;Li, Sai*;Xiang, Xi;Li, Zhiqiang;Liao, Xiaoxiang;Li, HuiStudy of conformational and functional changes caused by binding of environmental pollutant tonalide to human serum albumin,Chemosphere,2021，270，129431-42

2.Zhang, H ;Yan, JQ ;Mei, H ;Cai, SS;Li, S* ;Cheng, FR;Cao, J;He, B，High-drug-loading capacity of redox-activated biodegradable nanoplatform for active targeted delivery of chemotherapeutic drugs，REGENERATIVE BIOMATERIALS，2020，7: 4，359-369

3.Zhang, M;Zhang, XQ;Cai, SS;Mei, H;He, YM ;Huang,;Shi, WQ ;Li,S* ;Cao, J;He, B,Photo-induced specific intracellular release EGFR inhibitor from enzyme/ROS-dual sensitive nano-platforms for molecular targeted-photodynamic combinational therapy of non-small cell lung cancer，JOURNAL OF MATERIALS CHEMISTRY B，2020,8,35, ‏7931-7940;

4.Wan, SY;Zhang, BY ;Li, S* ;He, B;Pu, YJ,Combination of PEG-decorated black phosphorus nanosheets and immunoadjuvant for photoimmunotherapy of melanoma，JOURNAL OF MATERIALS CHEMISTRY B，，2020, 8,19, 4357, 2805-2813;

5.Zhao,Mingying;Wan,Shiyu;Peng,Xinyu;Zhang, BY ;Pan, QQ;Li,S* ;He, B ;Pu, YJ.Leveraging a polycationic polymer to direct tunable loading of an anticancer agent and photosensitizer with opposite charges for chemo-photodynamic therapy，JOURNAL OF MATERIALS CHEMISTRY B，2020, 8, 6, 1235-1244

6.Zhang, BY;Wan, SY;Peng, XY;Zhao, MY;Li, S;Pu, YJ ;He, B，Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity，JOURNAL OF MATERIALS CHEMISTRY B，2020，8, 17，3939-39482019,

7. Peng, XY ; Pan, QQ ; Zhang, BY; Wan, SY ; Li, S; Luo, K; Pu, YJ ; He, B，Highly Stable, Coordinated Polymeric Nanoparticles Loading Copper(II) Diethyldithiocarbamate for Combinational Chemo/Chemodynamic Therapy of Cancer，BIOMACROMOLECULES，2019，20 : 6 : 2372-2383

8. Zhou, Z ; Yuan, ZW ; Li, S ; Li, H; Wang, YQ ; Huang, QW ; Wang, C; Karahan, HE ; Henkelman, Big to Small: Ultrafine Mo2C Particles Derived from Giant Polyoxomolybdate Clusters for Hydrogen Evolution Reaction，SMALL，，2019: 15 : 1-11

9. X. Q. Zhang, S. S. Cai, Y. M. He, M. Zhang, J. Cao, H. Mei, S. Li and B. He，Enzyme-triggered deshielding of nanoparticles and positive-charge mediated lysosomal escape for chemo/photo-combination therapy，Journal of Materials Chemistry B，2019, 7, 4758--4762

10. Yixin Zhang, Song Luo, Yan Liang, Hai Zhang, Xinyu Peng,Bin He and Sai Li*, Synthesis, characterization, and property of biodegradable PEG-PCL-PLA terpolymers with miktoarm star andtriblock architectures as drug，Journal of Biomaterials Applications,2018,32，1139-1152

11. Xu, L ; Yang, ; Zhao, MY ; Gao, WX ; Zhang, H ; Li, S ; He, B ; Pu, YJ A reactive oxygen species-responsive prodrug micelle with efficient cellular uptake and excellent bioavailability，Synthesis and crystallization of well-defined biodegradable mikto arm star PEG-PCL-PLLA，JOURNAL OF MATERIALS CHEMISTRY B，2018，6，1076-1084

12. F. R. Cheng, Y. Chen, T. Su, H. Cao, S. Li, J. Cao, B. He, Z. W. Gua and X. L. Luo，Intracellular pH-induced fluorescence used to track nanoparticles in cells.J. Mater. Chem. B,2015,3, 5411-5414

13. Song Luo, Yixin Zhang, Jun Cao, Bin He, Sai Li*，Arginine Modified Polymeric Micelles as a Novel Drug Delivery System with Enhanced Endocytosis Efficiency，Colloids and Surfaces B: Biointerfaces2016, 7，15-23

14.Song Luo, Xinyu Peng, Ying Chen, Ting Su, Jun Cao, Sai Li* and Bin He，Synthesis, characterization, and crystallization of biodegradable poly(ε-caprolactone)-poly(L-lactide) diblock copolymers.E-polymers. 2015;15:15-23.

15.Yuanlin Li, Ting Su, Sai Li,* Yusi Lai, Bin He and Zhongwei Gu，Polymeric micelles with π–π conjugated moietyon glycerol dendrimer as lipophilic segments for anticancer drug delivery，Biomaterials Science，2014，2,775-783.

16.Hui Zheng , Sai Li∗, Yuji Pu a, Yusi Lai a, Bin He , , Zhongwei Gu，Nanoparticles Generated by PEG-Chrysin Conjugates for Efficient Anticancer Drug Delivery，EUR J PHARM BIOPHARM2014,87,454-460.

17.Shangfeng Pan, Song Luo, Sai Li,* Yusi Lai,a Yanyan Geng, Bin He* and Zhongwei Gu，Ultrasound accelerated gelation of novel l-lysine based hydrogelators，Chemical Communications2013.49.8045-8047

18.Ying Lei , Yusi Lai , Yuanlin Li , Sai Li ,∗, Gang Cheng, Dong Lia, Haiping Li ,Bin He,∗, Zhongwei Gu，Anticancer drug delivery of PEG based micelles with small lipophilic moieties.International Journal of pharmaceutics，2013.453.579-586

19.Jun Cao, Aijing Lua, Chenglong Li , Mengtan Cai, Yuanwei Chen,Sai Li ,∗, Xianglin Luo Effect of architecture on the micellar properties of poly( -caprolactone) containing sulfobetaines，Colloids and Surfaces B Biointerfaces，2013,112,35-41

20.Danna Yang, Lin Wang, Qiang Zhao, Sai Li*，Fabrication Of Single-Walled Carbon Nanotubes (SWNTs) Field-Effect Transistor (FET) Biosensor 2010 3RD INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING AND INFORMATICS (BMEI 2010), VOLS 1-7 ,1482-1485

21.Danna Yang, Lin Wang, Xiaoxian Zhang, Dongwei Wang, Zhiqiang Shen, Sai Li*, Alignment of Nanoscale Single-Walled Carbon Nanotubes Strands，NANO-MICRO LETTERS（3）3 ,146-152, 2011

22.Wang, Dongwei; Zhang, Xiaoxian; Yang, Danna，Li Sai*, Study of Preparation and Properties of Fire-retardant Melamine Formaldehyde Resin Foam Advanced Materials Research No .510, 634-638.2012

23.Sai Li, Yehai Yan, Ningyi Liu, Mary B. Chan-Park,* and Qing Zhang,Transfer Printing of Sub-Micron Patterns of Aligned Carbon Nanotubes onto Functionalized ElectrodesSmall，3, No. 4, 6 16 – 621,2007,

24. Sai Li, Ningyi Liu, Mary B Chan-Park, Yehai Yan, and Qing Zhang，Aligned Single-Walled Carbon Nanotube Patterns with Nanoscale Widths, Micronscale Lengths and Controllable Pitch，Nanotechnology18, 455302-455309.2007

获奖及发明专利

PCT/CN106765049B蒸气热泵及低压蒸气补焓增压利用的方法

个人奖励：

●2009、2014年获四川大学青年骨干教师奖

●2012、2016获全国化工设计大赛金奖指导老师

●2012、2013，2016、2020年度四川大学课堂教学质量优秀奖

●2012、2013、2014年大学生课外科技实践优秀指导教师奖

●2016年度四川大学唐立新教学名师奖

●2017年度四川大学圣华曦奖

2018年度四川省教学成果二等奖

●2019年度四川大学星火校友奖

论著

1、《近代化学基础》（国家面向21世纪课程教材）第三版下册，高等教育出版社出版，2015，

2、《工科物理化学教程》(国家十二五规划教材)，第三版，科学出版社，2012，